Publications

2020

60. Phosphine-Catalyzed Remote 1,7-Addition for Synthesis of Diene Carboxylates

Feng Jiaxu and Huang You*

ACS Catal., 2020, 10, 3541-3547. View

59. Organocatalyzed [3+3] Annulations for the Construction of Heterocycles

Zhu Yannan and Huang You*

Synthesis, 2020, 52, 1181-1202. View

58. Phosphine-Catalyzed (3 + 2)/(3 + 2) Sequential Annulation of γ-Vinyl Allenoates: Access to Fused Carbocycles

Feng Jiaxu, Chen Yingying, Qin Wenhui and Huang You*

Org. Lett., 2020, 22, 433-437. View

2019

57. Phosphine-catalyzed (3+2)/(2+3) sequential annulation involving a triple nucleophilic addition reaction of γ-vinyl allenoates

Feng Jiaxu and Huang You*

Chem. Commun., 2019, 55, 14011-14014. View

56. Phosphine-Catalyzed Divergent [4+3] Domino Annulations of CF3-Containing Imines with MBH Carbonates: Construction of Perfluoroalkylated Benzazepines

Chen Junlong, Yin Zhongmo and Huang You*

Org. Lett., 2019, 21, 7060-7064. View

55. Facile access to highly functionalized hydroisoquinoline derivatives via phosphine-catalyzed sequential [3+3]/[3+3] annulation

Li Ning, Jia Penghao and Huang You*

Chem. Commun., 2019, 55, 10976-10979. View

54. DABCO-mediated [3+3] annulation of para-quinamines: access to functionalized 1,2,4-triazinone derivatives

Zhu Yannan, Jin Hongxing and Huang You*

Chem. Commun., 2019, 55, 10135-10137. View

53. Nazarov Reagent: New Role for [4 + 2] Domino Benzannulation Reaction to Construct Polysubstituted Benzenes

Chang Meijia and Huang You*

Chem. Asian J. 2019, 14, 2588-2593. View

52. Phosphine-Catalyzed Domino [3 + 3] Cyclization of para-Quinamines with Morita–Baylis–Hillman Carbonates: Access to Hydroquinoline Derivatives

Jin Hongxing, Lai Jingxiong and Huang You*

Org. Lett., 2019, 21, 2843-2846. View

51. Sequential Phosphine-Catalyzed [4 + 2] Annulation of β′-Acetoxy Allenoates: Enantioselective Synthesis of 3-Ethynyl-Substituted Tetrahydroquinolines

Zhang Qinglong, Jin Hongxing, Feng Jiaxu, Zhu Yannan, Jia Penghao, Wu Chengzhou and Huang You*

Org. Lett., 2019, 21, 1407-1411. View

50. Phosphine Sequentially Catalyzed Domino 1,6-Addition/Annulation: Access to Functionalized Chromans and Tetrahydroquinolines with an Ethynyl-Substituted All-Carbon Quaternary Center

Zhu Yannan, Wang Dan and Huang You*

Org. Lett., 2019, 21, 908-912. View

2018

49. Phosphine-Catalyzed [3 + 2] Annulation of γ-Substituted Allenoates: Novel Access to Functionalized Cyclopentenes and Bicyclic[3, 3, 0]octene Derivatives

Li Erqing, Jin Hongxing and Huang You*

ChemistrySelect, 2018, 3, 12007-12010. View

48. Divergent Domino Reactions of Sulfur Ylides: Access to Functionalized Six- and Seven-Membered Nitrogen-Heterocycles

Chen Junlong, Jia Penghao and Huang You*

Org. Lett., 2018, 20, 6715-6718. View

47. DBU-Catalyzed Desymmetrization of Cyclohexadienones: Access to Vicinal Diamine-Containing Heterocycles

Jin Hongxing, Dai Changhang and Huang You*

Org. Lett., 2018, 20, 5006-5009. View

46. A Formal [5+1] Annulation Reaction of Sulfur Ylides and 2‐(1H‐indol‐2‐yl)phenols: Access to Indole‐Fused 4H‐benzo[e][1,3]oxazines

Jia Penghao and Huang You*

Adv. Synth. Catal. 2018, 360, 3044-3048. View

45. One-Pot Synthesis of Cyclopropanes from Methylene Azabicyclo[3.1.0]hexanes Obtained by Formal Sequential [1+2]- and [2+3]- Cycloaddition Reaction of Prop-2-ynylsulfonium Salts and Tosylaminomethyl Enones

Jia Penghao, Zhang Qinglong, Zhuge Yuzhou, Liwei Xingyue and Huang You*

Adv. Synth. Catal. 2018, 360, 438-443. View

 

2017

44. Phosphine-Catalyzed Sequential [4 + 3] Domino Annulation/Allylic Alkylation Reaction of MBH Carbonates: Efficient Construction of Seven-Membered Heterocycles

Chen Junlong and Huang You*

Org. Lett. 2017, 19, 5609-5612. View

43. Sequential [1+4]- and [2+3] Annulation of Prop-2-ynylsulfonium Salts: Access to Hexahydropyrrolo[3,2-b]indoles

Jia Penghao, Zhang Qinglong, Ou Qima and Huang You*

Org. Lett., 2017, 19, 4664-4667.‍  View

42. Divergent Synthesis of Hydropyridine Derivatives via Nitrogen Containing Lewis Base Mediated Regioselective [4+2] Cyclizations

Jin Hongxing, Li Erqing and Huang You*

Org. Chem. Front., 2017, 4,‍ 2216-2220. View

41. Phosphine-Catalyzed Intramolecular Rauhut-Currier Reaction: Enantioselective Synthesis of Hydro-2H-Indole Derivatives

Jin Hongxing, Zhang Qinglong, Li Erqing, Jia Penghao, Li Ning and Huang You*

Org. Biomol. Chem., 2017,15, 7097-7101. View (Highlighted by D. F. Taber, Org. Chem. Portal in 2018, July, 30th.)

40.  Phosphine-Mediated Sequential Annulation Reaction: Access to Functionalized Benzofurans and 4,5-Dihydrobenzofurans

Liang Ling, Dong Xuelin and Huang You*

Chem. Eur. J., 2017, 23, 7‍882-7886‍‍.  View  (Hot Paper)

39. A phosphine mediated sequential annulation process of 2-tosylaminochalcones with MBH carbonates to construct functionalized aza-benzobicyclo [4.3.0] derivates

Zhang Qinglong, Zhu Yannan, Jin Hongxing and Huang You*

Chem. Commun., 201‍7, 53, 3974-3977. View

38. [3 + 2]-Annulation of Prop-2-ynylsulfonium Salts: Access to Hydroindol-5-ones Containing a Methylthio Group

Jia Penghao, Zhang Qinglong, Jin Hongxing  and  Huang You*

Org. Lett. 2017, 19, 412-415. View

 

2016

37. Bifunctional-Phosphine-Catalyzed Sequential Annulations of Allenoates and Ketimines: Construction of Functionalized Poly-heterocycle Rings

Li Erqing, Jin Hongxing, Jia Penghao, Dong Xuelin and  Huang You*

Angew. Chem. Int. Ed. 2016, 55,‍ 11591-11594. View (Highlighted by Prof. List, B. and Grossmann, O. in Synfacts 2016, 12(11), 1199)

36. Phosphine Catalyzed [3+3]Domino Cycloaddition of Ynones and Azomethine Imines To Construct Functionalized Hydropyridazine Derivatives

Liang Ling and Huang You*

Org. Lett. 2016, 18, 2604-2607. View

35. Sequential Annulation Domino Reaction of Sulfur Ylides and α,β-Unsaturated Cyclic Ketimines: Synthesis of Cyclic 2-Alkenyl Aziridines

Jia Penghao and Huang You*

Org. Lett. 2016, 18, 2475-2478. View

34. One-Pot Synthesis of Polysubstituted Benzenes through a N,N-dimethyl-4-aminopyridine (DMAP)-Catalyzed [4+2] Benzannulation of 1,3-Bis(sulfonyl)butadienes and γ-Substituted Allenoates

Chang Meijia, Wu Chengzhou, Zheng Jie and Huang You*

Chem. Asian J. 2016, 11, 1512-1517. View

 

2015

33. DABCO-Mediated [4 + 4]-Domino Annulation: Access to Functionalized Eight-Membered Cyclic Ethers

Liang Ling, Li Erqing, Dong Xuelin and Huang You*

Org. Lett. 2015, 17, 4914-4917. View

32. Highly Enantioselective Intermolecular Cross Rauhut-Currier Reaction Catalyzed by a Multifunctional Lewis Base Catalyst

Dong Xuelin, Liang Ling, Li Erqing and Huang You*

Angew. Chem. Int. Ed. 2015, 54, 1621-1624.  View  (Hot Paper, Highlighted by Prof. List, B. and Höfler, D. in Synfacts 2015, 11(3), 0325)

31. Divergent Phosphine-Catalyzed [2+4] or [3+2] Cycloaddition Reactions ofγ-Substituted Allenoates with Oxadienes

Li Erqing, Chang Meijia, Liang Ling and Huang You*

Eur. J. Org. Chem. 2015, 710-714. View  (Hot Paper

 

2014

30. A Sulfur Ylides-Mediated Domino Benzannulation Strategy to Construct Biaryls, Alkenylated and Alkynylated Benzene Derivatives

Gao Fei and Huang You*

Adv. Synth. Catal. 2014, 356, 2422-2428.‍ View

29. Phosphine-Catalyzed Sequential Annulation Domino Reaction: Rapid Construction of Bicyclo[4.1.0]heptene Skeletons

Zheng Jie, Huang You* and Li Zhengming

Chem. Commun., 2014, 50, 5710-5713. View

28. Phosphine-catalyzed Domino Reaction: A Novel Sequential [2+3] and [3+2] Annulation Reaction of γ-Substituent Allenoates to Construct Bicyclic[3, 3, 0]octene Derivatives.

Li Erqing and Huang You*

Chem. Commun., 2014, 50, 948-950. View

27. Sequential Catalyst Phosphine/Secondary Amine-Promoted [1+4]/ Rearrangement Domino Reaction for the Construction of (2H)-Pyrans and 2-oxabicyclo[2.2.2]oct-5-ene Skeletons

Xie Peizhong, Yang Jie, Zheng Jie and Huang You*

Eur. J. Org. Chem., 2014, 1189-1194. View

26. Phosphine-Catalyzed Domino Reaction: A Novel Method Access to Functionalized Bicyclic Skeletons

Li Erqing and Huang You*

Chem. Eur. J., 2014, 20, 3520‍-3527. View

25. Phosphine Initiated Domino Reaction: A Convenient Method for the Preparation of Spiro-cyclopentanones

Liang Ling, Li Erqing, Xie Peizhong and Huang You*

Chem. Asian J. 2014, 9, 1270-1273. View

24. Phosphine-Catalyzed Sequential [2 +3] and [3 + 2] Annulation Domino Reaction of γ- Benzyl Substituted Allenoates with α,β-Unsaturated Ketimines To Construct Aza-bicyclo[3, 3, 0]octane Derivatives

Li Erqing, Jia Penghao, Liang Ling and Huang You*

ACS Catal. 2014, 4, 600-603. View

23. A simple and highly efficient procedure for construction of quaternary carbons centers by tributylphosphine catalyzed bis-Michael addition

Xu Da-Zen, Zhan Ming-Zhe and Huang You*

Tetrahedron 2014, 70,176-180. View

 

2013

22. One step Synthesis of Benzoxazepine Derivatives via a PPh3 Catalyzed aza-MBH Domino Reaction between Salicyl N-tosylimines and Allenoates

Zhao Hongxia, Meng Xiangtai and Huang You*

Chem. Commun., 2013, 49, 10513-10515. View (Highlighted by Prof. Snieckus, V and Guimarães, K. G. in Synfacts 2014, 10(1), 0027)

21. Phosphine-Catalyzed Domino Reaction: An Efficient Method for the Synthesis of Bicyclo[3.2.0]heptenes Skeleton

Zheng Jie, Huang You* and Li Zhengming

Org. Lett. 2013, 15, 5758-5761. View

20. Phosphine-Catalyzed Domino Benzannulation: An Efficient Method to Construct Biaryl Skeletons

Zheng Jie, Huang You* and Li Zhengming

Org. Lett. 2013, 15, 5064-5067. View

19. Phosphine-Catalyzed [4+2] Annulation of gamma-Substituent Allenoates: Facile Access to Functionalized Spirocyclic Skeletons

Li Erqing, Huang You*, Liang Ling and Xie Peizhong

Org. Lett. 2013, 15, 3138-3141. View

18. Tunable Phosphine-Mediated Domino Reaction: Selective Synthesis of 2,3-Dihydrofuransand Biaryls

Xie Peizhong, Li Erqing, Zheng Jie, Li Xin, Huang, You* and Chen Ruyu

Adv. Synth. Catal. 2013, 355, 161-169.  View  (Hot Paper)

17. Phosphine-Catalyzed Rauhut-Currier Domino Reaction: A Facile Strategy for the Construction of Carbocyclic Spirooxindoles Skeleton

Hu Chongchong, Zhang Qinglong and Huang You*

Chem. Asian J. 2013, 8 , 1981-1984‍. View 

 

16. Tuning Catalysts to Tune the Products: Phosphine-Catalyzed Aza-Michael Addition Reaction of Hydrazones with Allenoates

Li Erqing, Xie Peizhong, Yang Lihua, Liang Ling and Huang You*

Chem. Asian J. 2013, 8 , 603-610. View

15. Domino Cyclization Initiated by Cross-Rauhut-Currier Reactions

Xie Peizhong and Huang You*

Eur. J. Org. Chem. 2013, 6213-6226.‍ ‍View

14. Sulfur Ylides Participating Domino Cyclization Reaction

Li Gongchun, Wang Liye and Huang You*

Chin. J.Org. Chem. 2013, 33, 1900-1918.

 

2012

13. Phosphine-catalyzed Domino Reaction: an Efficient Method for the Synthesis of Highly Functionalized Spirooxazolines

Yang Lihua, Xie Peizhong, Li Erqing, Li Xin, Huang, You* and Chen Ruyu

Org. Biomol. Chem. 2012, 10, 7628-7634. View

12. Phosphine-Catalyzed Rauhut-Currier Domino Reaction: A Facile Strategy for the Construction of Highly Functionalized Cyclopentene

Hu Chongchong, Geng Zhishuai, Ma Jianze, Huang You* and Chen Ruyu

Chem. Asian J. 2012, 7 , 2032-2035.  View

11. Phosphine-mediated Domino Benzannulation Strategy for the Construction of Highly Functionally Multi-aryl Skeletons

Xie Peizhong, Huang, You* and Chen Ruyu

Chem. Eur. J. 2012, 18, 7362-7366. View ( Most accessed article 2012. 5 )

10. Organocatalytic domino reaction of salicyl N-thiophosphoryl imines and methyl vinyl ketone initiated by an aza MBH reaction with bifunctional phosphine catalysts

Meng Xiangtai, Xie Peizhong, Huang You* and Chen Ruyu

RSC Adv., 2012, 2, 8104-8109. View

9. Phosphine-Catalyzed Domino Reaction for the Synthesis of Conjugated 2,3-Dihydrofurans from Allenoates and Nazarov Reagents and the Mechanism Investigation

Xie Peizhong, Lai Wenqing, Geng Zhishuai, Huang You* and Chen Ruyu

Chem. Asian J. 2012, 7 , 1533-1537. View

 

2011

8. Bifunctional phosphine-catalyzed Cross-Rauhut-Currier/Michael/Aldol Condensation Triple Domino Reaction: Synthesis of Functionalized Cyclohexenes

Xie Peizhong, Huang You*, Lai Wenqing, Meng Xiangtai and Chen Ruyu

Org. Biomol. Chem. 2011, 9, 6707-6714. View

7. Domino Reaction for the Chemo- and Stereoselective Synthesis of Trans-2,3-Dihydrobenzofurans from N-Thiophosphinyl Iimines and Sulfur Ylides

Xie Peizhong, Wang Liye, Yang Lihua, Li Erqing, Ma Jianze, Huang You* and Chen Ruyu

J. Org. Chem. 201176, 7699-7705.‍  View

6. Substrate-Controlled Phosphine-Catalyzed Domino Reactions of Activated Conjugated Dienes: Highly  Diastereoselective Synthesis of Bicyclic Skeletons

Ma Jianze, Xie Peizhong, Hu Chongchong, Huang You* and Chen Ruyu

Chem. Eur. J. 2011, 17, 7418-7422. View  (Hot Paper)

5. N-Heterocyclic Carbene-Catalyzed (NHC) Three-Component Domino Reactions: Highly Stereoselective  Synthesis of Functionalized Acyclic ε-Ketoesters

Ma Jianze, Huang You* and Chen Ruyu

Org. Biomol. Chem. 2011, 9, 1791-1798. View

 

2010

4. Phosphine-Catalyzed Domino Reaction: Highly Stereoselective  Ssynthesis of Trans-2,3-Dihydrobenzofurans  from Salicyl  N-Thiophosphinyl Imines and Allylic Carbonates

Xie Peizhong, Huang You* and Chen Ruyu

Org Lett. 2010, 12, 3768-3771. View

 

2009

3. PPh3-Catalyzed Domino Reaction: A Facile Method for the  Synthesis of Chroman Derivatives

Meng Xiangtai, Huang You*, Zhao Hongxia, Xie Peizhong, Ma Jianze and Chen Ruyu

Org. Lett. 2009, 11, 991-994. View

2. Bifunctional Phosphine-Catalyzed Domino Reaction: Highly Stereoselective Synthesis of cis-2,3-Dihydrobenzofurans  from Salicyl N-Thiophosphinyl Imines and Allenes

Meng Xiangtai, Huang You* and Chen Ruyu

Org Lett. 2009, 11, 137-140. View

 

2008

1. A Novel Selective aza-Morita-Baylis-Hillman (aza-MBH)  Domino Reaction and aza-MBH Reaction of N-Sulfonated Imines with Acrolein Catalyzed by a Bifunctional Phosphine Organocatalyst

Meng Xiangtai, Huang You* and Chen Ruyu

Chem. Eur. J. 2008, 14, 6852-6856. View  (Hot Paper, Most accessed article 2008. 7)